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$13M Grant Will Support Research to Better Understand Chronic Lung Disease and Inflammation

photos of the three researchers in their labs

A team of UII Health researchers have received $13 million in funding from the National Heart, Lung, and Blood Institute to study mechanisms of inflammation in the lungs, specifically how the immune system is regulated by the lung endothelium. The program director for the grant is Dolly Mehta, UIC professor and interim head of the Department of Pharmacology and Regenerative Medicine at the University of Illinois College of Medicine. The research team consists of six investigators who will lead three separate project grants, with Dr. Mehta leading one project and the other two under the leadership of Asrar Malik, professor of pharmacology and regenerative medicine, and Dr. Jalees Rehman, professor and head of the Department of Biochemistry and Molecular Genetics. The researchers hope that their projects will forge a path to treatments for conditions such as chronic obstructive pulmonary disorder, pulmonary fibrosis and acute respiratory distress disorder, a common and serious complication of COVID-19.